4,4,5,5-Tetramethyl-1,3,2-dioxaborolane is a Boration reagent used for the borylation at the benzylic C-H bond of alkylbenzenes in the presence of a palladium catalyst to form pinacol benzyl boronate. Also used in the Hydroboration of alkyl or aryl alkynes and alkenes in the presence of transition metal catalysts, Asymmetric hydroboration of 1,3-enynes to form chiral allenyl boronates, and coupling with aryl iodides in the presence of a copper catalyst to form aryl boronates.